|
 
 |
| LETTER TO EDITOR |
|
| Year : 2023 | Volume
: 14
| Issue : 1 | Page : 87 |
|
Cancerous Patient, COVID-19 Vaccination, Blood Viscosity and Stroke-Like Complication
Beuy Joob1, Viroj Wiwanitkit2
1 Private Academic Consultant, Bangkok, Thailand
2 Honorary Professor, Department of Community Medicine, Dr DY Patil Vidhyapeeth, Pune, Maharashtra, India
| Date of Submission | 22-May-2021 |
| Date of Decision | 25-May-2021 |
| Date of Acceptance | 29-May-2021 |
| Date of Web Publication | 22-Jun-2023 |
Correspondence Address:
Beuy Joob
Private Academic Consultan, Bangkok
Thailand
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijpvm.ijpvm_217_21
How to cite this article:
Joob B, Wiwanitkit V. Cancerous Patient, COVID-19 Vaccination, Blood Viscosity and Stroke-Like Complication. Int J Prev Med 2023;14:87 |
Dear Editor,
The coronavirus disease 2019 (COVID-19) vaccine is the hope for the management of the COVID-19 outbreak. At present, the COVID-19 vaccine is already in use in several countries. An important concern is the adverse effect of vaccination. There are many possible adverse effects of the COVID-19 vaccine including vascular complication. The possible neurological complication due to the COVID-19 vaccine is an important present consideration.[1] There are many recent reports on neurological incidences including stroke-like complication after vaccination.
In a recent local report from Indochina (https://www.reuters.com/world/asia-pacific/thailand-sticks-with-sinovac-vaccine-after-cases-stroke-like-side-effects-2021-04-21/), a post-COVID-19 vaccination stroke-like incidence occurs. A patient with underlying breast cancer is a member of all six affected cases, there is a patient with underlying breast cancer. It is questionable on the exact pathomechanism of the incidence. Indeed, a possible explanation of post-vaccination vascular complication is the change of blood viscosity. The COVID-19 vaccination can result in a change of blood viscosity due to an increased level of immune elements.[2] An increase in immunoglobulin is confirmed as a possible cause of increased blood viscosity.[3] A cancer patient, including the one with breast malignancy, might have a background high-blood viscosity.[4] Therefore, after vaccination, a hyperviscosity might occur, and it might result in a stroke-like event. For COVID-19 vaccination, it should be used with precaution in a patient with the underlying malignancy.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
| References | |  |
| 1. | Lu L, Xiong W, Mu J, Zhang Q, Zhang H, Zou L, et al. The potential neurological effect of the COVID-19 vaccines: A review. Acta Neurol Scand 2021. doi: 10.1111/ane. 13417. Online ahead of print.  |
| 2. | Saadat S, Tehrani ZR, Logue J, Newman M, Frieman MB, Harris AD, et al. Binding and neutralization antibody titers after a single vaccine dose in health care workers previously infected with SARS-CoV-2. JAMA 2021;325:1467-9. |
| 3. | Dalakas MC. High-dose intravenous immunoglobulin and serum viscosity: Risk of precipitating thromboembolic events. Neurology 1994;44:223-6. |
| 4. | von Tempelhoff G-F, Schönmann N, Heilmann L, Pollow K, Hommel G. Prognostic role of plasmaviscosity in breast cancer. Clin Hemorheol Microcirc 2002;26:55-61. |
|
Search Pubmed for