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Year : 2022  |  Volume : 13  |  Issue : 1  |  Page : 109

SARS-CoV-2: Review of conditions associated with severe disease and mortality

School of Public Health, University of Saskatchewan, Saskatoon, SK, Canada

Correspondence Address:
Joshua Eyitemi
Representative of the Alumni Group, University of Saskatchewan, School of Public Health, 104 Clinic Place, Saskatoon, SK S7N 2Z4
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpvm.IJPVM_640_20

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The 2019 Coronavirus Virus Disease (COVID-19) represents a global public health challenge in the twenty-first century. As of June 2020, the virus had spread across 216 countries across the globe. This paper aims to analyze and identify those existing comorbidities among COVID-19 patients that represent potential risk factors for COVID-19 complications, severe illness, and death. Multiple database resources were searched. The resources include the University of Saskatchewan library USearch, Google Scholar, PubMed, Medline, and the Google search engine. Thirty-seven articles, which included 15 different types of chronic diseases, were selected. Among the reviewed diseases and conditions, cancer, diabetes, lymphopenia, hypertension, kidney disease, smoking, chronic obstructive pulmonary disease (COPD), and organ transplant were found to represent potential risk factors for COVID-19 complications, severe illness, and death. Other conditions that require further research as to whether they predispose subjects to severe illness and death include coronary artery disease, cerebrovascular disease, valvular heart disease, gastrointestinal diseases, HIV/AIDS, asthma, and liver disease. In conclusion, this article explains the association between diseases mentioned above and the severity of COVID-19 and clearly shows the population at risk. This paper will help government bodies and decision-makers prioritize resources for these populations to reduce mortality rates and overall quality of life.

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